Generic Name: Tramadol

Brand name: Ultram, Ultram ER, Amadol, Tramadolor

Class of drug: Narcotic (opioid) analgesic.

Mechanism of action: Most likely produces analgesia by binding to opioid receptors. Also inhibits reuptake of norepinephrine and serotonin.

Indications/dosage/route: Oral only.

• Moderate to moderately severe pain

Adults: 50-100 mg q4-6h prn. Maximum: 400 mg/d.

Adjustment of dosage

• Kidney disease: Creatinine clearance <30 mL/min: 50-100 mg q12h. Maximum: 200 mg/d.
• Liver disease (cirrhosis): 50 mg q12h.
• Elderly: Maximum daily dose of 300 mg in patients >75 years.
• Pediatric: Safety and efficacy of tramadol have not been estab-
• lished in children <16 years. Read the rest of this entry »

This medication is one of the most widely spread and popular drugs all over the world. The main proof is that it may be bought without a doctor’s prescription in any pharmacy online as well as in ordinary drugstore. Even in places where it is a very serious question, Paracetamol is freely sold and more than that without any limitations. This, on one hand, says about effectiveness of the medication and on the other hand, about its safety.

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