KAVA-KAVA COMPOUNDS

Kava lactones (kava pyrones, 5-12%): chief components include (+)-kavain, dihydrokavain (marindinine), (+)-methysticin, dihydromethysticin, yangonine, desmethoxyyangonin

Chalcones: including flavokavin A and B

KAVA-KAVA EFFECTS

The kava pyrones in the drug have centrally muscle-relaxing, anticonvulsive and antispasmodic effects. The herb also contains hypnotic/sedative, analgesic and psychotropic properties contributing to its use for anxiety and insomnia.

The centrally muscle-relaxing, analgesic and anticonvulsive action of the kava pyrones, kavain, dihydrokavain, dihydromethysticin and (+/-) kavain (synthetic kava pyrone) is attributed to the interaction with ion channels. The interaction consists of fast and specific inhibition of voltagedependent sodium channels and reduction of currents through voltage-activated sodium and calcium channels (Friese, 1998; Gleitz, 1995; Gleitz, 1996; Schirrmacher, 1999). The paralysis effect of Kava on neuromuscular transmission and muscle contractility is similar to that of local anesthetics (Jameison, 1989; Singh, 1983). The lipid soluble extract (kava resin) decreases spontaneous motility and motor control (Jamieson, 1989). Read the rest of this entry »

KAVA-KAVA TRADE NAMES
Kava Kava (available from numerous manfacturers) Alcohol Free Kava Kava, Kava Kava Power, Kava Kava Premium, Kava Kava Root

KAVA-KAVA DESCRIPTION
Medicinal Parts: The medicinal parts are the peeled, dried, cut rhizome, which has normally been freed from the roots, and the fresh rhizome with the roots.

Flower and Fruit: The plant has numerous small flowers in spike-like inflorescences 3 to 9 cm long.

Leaves, Stem and Root: The plant is a 2 to 3 m high, erect dioecious bush. The leaves are very large, measuring 13 to 28 cm by 10 to 22 cm. They have a deeply cordate base and 9 to 13 main ribs that are slightly soft on the undersurface. The stipules are large. The plant has a massive, 2 to 10 kg, branched and very juicy rhizome with many roots. They are blackish-gray on the outside and whitish on the inside. The fracture is mealy and somewhat splintery. The central portion is porous with irregularly twisted thin woody bundles, separated by broad medullary rays, forming meshes beneath the bark. Read the rest of this entry »

Pronunciation: lor-A-ze-pam
Chemical Abstracts Service Registry Number: 846-49-1
Formal Names: Ativan, Temesta
Type: Depressant (benzodiazepine class).
Federal Schedule Listing: Schedule IV (DEA no. 2885)
USA Availability: Prescription
Pregnancy Category: D

Lorazepam [Ativan, Temesta] Uses. This antianxiety drug is also known for its sedative properties and is used to promote sleep and to fight convulsions. The substance is given to treat status epilepticus, a dangerous condition in which people have one epileptic seizure after another, back-to-back. It can reduce and sometimes even eliminate vomiting from cancer chemotherapy.  Lorazepam has been used to treat LSD and methamphetamine overdose and has been a standard medicine to help alcoholics through the alcohol withdrawal syndrome. Recreational sedative users report euphoria from lorazepam. When given experimentally in combination with other drugs, it has helped reduce depression. In contrast, experimentation using motion picture excerpts to evoke particular emotions found that lorazepam may reduce happy feelings and increase unhappy ones. One study found that lorazepam worked as well as alprazolam for treating panic attacks, and a case report tells of success in treating mania. Lorazepam has been used to cure both catatonia (in which people are frozen in place) and akathisia (compulsive moving around). Patients being prepared for surgery receive the drug to calm them and to cloud their memory of the event. Read the rest of this entry »

Anti-anxiety drugs, or “anxiolytics,” are powerful central nervous system (CNS) depressants that can slow normal  brain function. They are often prescribed to reduce feelings of tension and anxiety, and/or to bring about sleep. Anti-anxiety medications are among the most abused drugs in the United States, obtained both legally, via prescription, and illegally, through the black market. These drugs are also known as sedatives.

The drugs associated with this class of substance-related disorders are the benzodiazepines [such as diazepam (Valium),  chlordiazepoxide (Librium), alprazolam (Xanax), triazolam (Halcion), and estazolam (ProSom)], the barbiturates [such as Seconal and pentobarbital (Nembutal)], and barbiturate - like substances including Quaalude, Equanil, and Doriden. Any of these drugs is capable of producing wakeful relief from tension, or sleep, depending upon dosage. Some non-psychiatric uses of anti-anxiety medications include treatment and prevention of seizures, muscle relaxants, anesthetics, and drugs to make other anesthetics work more effectively (known as “adjuvants”). Read the rest of this entry »

There are hundreds of phobias. Here are a few:

Agoraphobia:
One of the most common phobias, agoraphobia affects women far more than men (roughly two-thirds of sufferers are female). Literally the fear of open spaces, agoraphobia is better known as the fear of being alone in a crowd, or in any place such as a theatre or a church or a shopping centre where escape might appear to be difficult. Such avoidance behaviour can lead to agoraphobia’s extreme effect: the trapping of a person in her home. Read the rest of this entry »

A client wrote:
“I’m terrified something awful is happening to me. Almost
every day I become really scared. I shiver, my chest hurts, my
throat goes dry, I feel dizzy, faint and frightened for fifteen or
twenty minutes of hell. When this happens I feel sure I’m going
insane, or I’m going to die. My doctor says there’s nothing
wrong, that I’m “just” having a panic attack.
She wouldn’t be so complacent if this happened to her! How
can this be ‘just in my head’?”

The pharmaceutical companies would like you to believe that panic attacks arise from something biological … and therefore can be fixed with a pill.  Read the rest of this entry »

Panic disorder is a widely spread anxious state that affects about 4% of all population. Women suffer from it six times more often than men. The typical start of a panic disorder is usually observed in adolescence and in the beginning of a mature age. Read the rest of this entry »

Buy Alprazolam online without prescription:

Buy Xanax / Tafil [Brand Alprazolam] online without prescription:

Buy Xanor [German Brand Alprazolam] online without prescription:

What is the difference between Xanax and Xanax Retard? Is it important for a patient taking 1.0 mg before going to sleep?

Action of Xanax comes into force in 1-2 hours and lasts during 16 hours. Xanax Retard as a rule is taken by 1mg in 24 hours.

My doctor has prescribed me Xanax Retard but I could not find it in our drugstore. They offered me Alprazolam instead. I am not very clear in medicaments; however the doctor prescribed me Xanax Retard because of its convenient use (one time before going to bed) as a result of a long-term action. And what about Alprazolam?

As a matter of fact, Alpazolam is a generic drug of Xanax that is why their properties are almost similar. Read the rest of this entry »

A lot of people do not know exactly what generic drugs mean. This misunderstanding often results in underestimation of generics and people may not use the opportunity to save more money by buying drugs cheaper or on the contrary consider them to be exactly the same as brand drugs and forget about their peculiarities which may lead to a converse effect. Let us make clear some of characteristics of generics to answer the most frequently asked questions as for them and help people to grasp the drugs better.

Generic drugs – what are they?

Generics contain the same active ingredients as drugs that are brand – names. The USA government has certified them as ones which are equivalent to the brand-name drugs. The main role is played by the active ingredient that is the actual medicine aimed to treat diseases. Generic name may be seen in brackets of almost every drug after its brand name. It is actually the title of the active ingredient. Let us take Tylenol as an example. Its generic name is acetaminophen. You always have got a choice – you may buy the pharmacy brand of acetaminophen or acetaminophen of any other company. Such sign as ® appears to indicate a registered trademark. What does it mean if we see this sign? It means that the producer has a copyright protection on this name as in case for Tylenol, for example.

For better understanding, let us take another example with very popular medicine nowadays – Valium. Valium is the brand name of a drug used to deprive of anxiety and feeling of worry. Diazepam – is the generic name. Valium was the first that appeared on the pharmacy market and only the brand name existed and was possible. When the exclusive rights of the original producers on this drug had come to an end – other companies got the opportunity to manufacture the drug Diazepam and sell it on the market. Of course, this drug has the same active ingredients and the same characteristics but other producers cannot name their drug as Valium because this name belongs to the original manufacturer of this medication. The generic manufactures just call it by the generic name that is Diazepam.

What is the difference between generic Drugs and Brand Drugs?

It is clear that both these drugs, Generic and Brand, have one and the same active ingredient, but still there is the difference in their inactive ingredients which are chosen by manufactures and which may give the drug its bulk as well as taste or even change its look. That is the reason why generics may have another taste and look than their brand drugs. Despite of the fact that inactive ingredients do not change the medicine itself – some patients may find out different reactions of their organisms to inactive ingredients effect. For instance, some producers may have a yellow tinge for the color of the medicine while others use a red one. A patient who has an allergy to a certain tinge may react differently to various drugs according to their colors. That is the case when your doctor assures that you should take only brand drug to escape some unequal reaction of your organism despite of the fact, that a generic is available. Then your doctor will mention about this in his prescription to notify a pharmacist of possible negative effect and necessity to take exactly brand drug. If you look closer at your prescription that was given to you by your doctor – you’ll notice a little box with the letters “daw” or “dispense as written” in the bottom of the list which means that your pharmacist should not suggest you generic but only a brand drug.

1. If it is the first time you’ve had an attack, try to define the emotional factors which could provoke a strong feeling of anxiety. Find the connection between your feelings, state and antecedent events. Analyze the problem and try to solve it.
2. Try not to develop a limiting conduct even if your panic attack occurred on the street or in the transport. Keep on using a transport and have as active way of life as it is possible.
3. Having the first signs of the panic attack take some benzodiazepines, for example Xanax, Diazepam, Valium, Alprazolam or other. Bear this medication with yourself. After taking the medication, effect is felt in about 20-30 minutes. Such medications as Xanax may stop the attack in full or smooth away the symptoms. With a help of the medication you will stand the panic attack in a benign.
4. If the panic attack happened in a public place – try to take the medication quickly and sit calmly about a half an hour till you feel the sedative action of the drug. If you have not taken the medicine with yourself then try to relax at first, sit for some time and then go back home or to your office (asking not to disturb you). If you still feel bad - call for an Ambulance.
5. During the panic attack try to breathe evenly and calmly even if you want to breathe more frequently. A tachypnoe may provoke a hyperventilation syndrome when with an increase of breathing frequency - a feeling of fear and anxiety increases and as a result they in their turn make you breathe more and more frequently and so on.
6. If your hands and feet grow cold during the panic attack, try to warm them using a hot water for example. You may also take a hot bath if you are at home at that moment. But you should do it only if you have your extremities growing cold however if you have a fever and high blood pressure - you should not do it! This method also helps to stop quickly an attack.
7. It is also not unreasonable to tell about your state to someone among your close relatives who may support you.